Letter re: "Cyclosiloxanes produce fatal liver and lung damage in mice".
نویسنده
چکیده
Comments on Lieberman's article: Cyclosiloxanes Produce Fatal Liver and Lung Damage in Mice. Environ Health Perspect 107:161-165
منابع مشابه
Response from lieberman and colleagues
Respond on comments on Lieberman's article: Cyclosiloxanes Produce Fatal Liver and Lung Damage in Mice. Environ Health Perspect 107:161-165
متن کاملLetter re: "Cyclosiloxanes produce fatal liver and lung damage in mice".
with 'H nuclear magnetic resonance (NMR) technique using an internal control (5). Blood samples from animals given feed without siloxanes showed no signals originating from the silicones tested. In all blood samples from animals given feed with siloxanes, they were detected. In samples from animals given feed with PDMS, the mean concentration (± standard deviation) of siloxanes of 26 ± 14 pg/cm...
متن کاملLetter re: "Cyclosiloxanes produce fatal liver and lung damage in mice".
with 'H nuclear magnetic resonance (NMR) technique using an internal control (5). Blood samples from animals given feed without siloxanes showed no signals originating from the silicones tested. In all blood samples from animals given feed with siloxanes, they were detected. In samples from animals given feed with PDMS, the mean concentration (± standard deviation) of siloxanes of 26 ± 14 pg/cm...
متن کاملLetter re: "Cyclosiloxanes produce fatal liver and lung damage in mice".
LD50 for the distillate was 28 g/kg body weight; for D4, a component of the mixture , the LD 0 was 6-7 g/kg. According to the first edition of the now classical Casarett's and Doull's Toxicology (3), such values are not characteristic for highly toxic compounds. As a matter of fact, agents having an LD50 of 5-15 g/kg are usually classified as slightly toxic, and those having an LD50 of > 15 g/k...
متن کاملCyclosiloxanes produce fatal liver and lung damage in mice.
To examine the toxicity of cyclosiloxanes (CSs), the predominant low molecular weight cyclic silicones found in breast implants, we injected female CD-1 mice intraperitoneally with different doses of distillate (3.5-35 g/kg body weight) containing cyclosiloxane D3 (hexamethylcyclotrisiloxane; CS-D3), cyclosiloxane D4 (octamethylcyclotetrasiloxane; CS-D4), cyclosiloxane D5 (decamethylcyclopentas...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Environmental Health Perspectives
دوره 107 شماره
صفحات -
تاریخ انتشار 1999